HOXA5 . However, its intricate etiology and pathological mechanisms are still unclear. BioGPS Spotlight on the Sheep Gene Expression Atlas. Citations. high expression. Transcriptome and pathway profiling analyses of cells expressing HOXA1 reveal up-regulation of factors involved in diverse cytokine pathways that include the TGF signaling axis, which we further demonstrate to be required for HOXA1-mediated cell invasion. mRNA expression profiles for the NCI-60 panel of cancer cell lines. This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. Rare persister cells are already present in nave T-ALL populations, and the reversibility of the phenotype is suggestive of an epigenetic mechanism. English. To identify EVT-specific gene expression signatures in trophoblast cell lines, we calcuted differentially expressed genes between pre-defined groups based on the distinct origins of the five trophoblast cell lines under investigation. Dataset: CCLE Cell Line Gene Expression Profiles: Category: transcriptomics Type: cell line: Description: A subline of the M-07 human megakaryoblastic leukemia cell line. You can access the database here: http://157.82.78.238/refexa/main_search.jsp Cite 2 Recommendations 25th Sep,. English Espaol Portugus Franais Italiano Svenska Deutsch. Depletion of CKS2 in Y79 retinoblastoma cell line led to reduced cell proliferation, delayed DNA replication and decreased clonogenic growth. Identifiers; Aliases: IL17A, CTLA8, IL-17, IL-17A, IL17, CTLA-8, interleukin 17A, ILA17 . The effect of trypsin-2 on human tongue squamous cell carcinoma cell line gene expression Species: human Samples: 6 . A number of miRNAs have been found and their expression profiles have been examined by means of various microarray systems and real-time polymerase chain reaction (PCR) systems. HEK 293T . Filter Showing 1 to 20 of 74 entries Previous 1 2 3 4 Next A look back at 2016 for BioGPS. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000007) Similar Terms: Downloads & Tools Differential gene expression profile of . Frequent questions. Type. BioGPS has thousands of datasets available for browsing and which can be easily viewed in our interactive data chart. CCLE Cell Line Gene Expression Profiles: Category: transcriptomics Type: cell line: Similar Terms: Downloads & Tools: Genes. . (2017). Nowadays, there has been extensive interest in cellular senescence in RIF, and its involvement in endometrial immune characteristics during the window of implantation (WOI) has captured scholars . Stem . Recurrent implantation failure (RIF) is an extremely thorny issue in in-vitro fertilization (IVF)-embryo transfer (ET). Entrez Gene Summary for LOC125467757 Gene. cell type or tissue Gene Sets 74 sets of genes with high or low expression in each cell type or tissue relative to other cell types and tissues from the BioGPS Mouse Cell Type and Tissue Gene Expression Profiles dataset. Affiliations. WikiZero zgr Ansiklopedi - Wikipedia Okumann En Kolay Yolu . Gene expression search. Using unsupervised and supervised machine learning methods to identify survival-associated gene signatures, a multivariable model of survival was constructed. This database provides gene expression profiles from various human organs and cells. Analysis of the genome of cell cultures of normal ovarian cells and ovarian cancer was carried out with the BioGPS tool [29], as well as the KEGG database [30]. Although extensive similarity was noted between the expression profiles, more than 500 . Transcription profiling of human tongue squamous cell carcinoma (SCC) Later diagnosis changed to adenocarcinoma, first aneuploid, continuously cultured human cell line. Home . Derived from: axillary node. A better molecular characterization of breast cell lines (BCL) may help discover new markers to apply to tumour samples. BioGPS Cell Line Gene Expression Profiles: Category: transcriptomics Type: cell line: Description: Human chronic myeloid leukemia in blast crisis established from the pleural effusion of a 53-year-old woman with chronic myeloid leukemia (CML) in blast crisis in 1970. We profiled the mRNA expression level of these samples and classified probe sets into epithelial genes which were those genes with present calls in at least 50% of the samples. MOLT4: NCI 460: NCI H226: NCI H23: NCI H322M ringwald@informatics.jax.org PMID: 22847375 PMCID: PMC3469763 DOI: 10.1007/s00335-012-9408- Abstract Affiliations. Validation of BMP7 as a key gene involved in secondary resistance was performed using cultures of cell line. Dataset. Category. More than 300,000 transcripts derived from at least 45,000 different genes were analyzed. Geiger Laboratory; Weizmann Institute of Science; Ma'ayan Laboratory of Computational Systems Biology; Icahn School of Medicine at Mount Sinai; We performed gene and protein expression profiling of 31 BCL using whole . Here we modeled T-ALL resistance to Notch inhibition, identifying 'persister' cells that readily expand in the presence of gamma secretase inhibitor (GSI) and the absence of Notch signaling. BioGPS Cell Line Gene Expression Profiles: Category: transcriptomics Type: cell line: Description: Established from a human primary embryonal kidney transformed by adenovirus type 5. Medical Information Search. These observations are . The first step to perform such experiments is to select an appropriate cell line to serve as an in vivo model. BioGPS Cell Line Gene Expression Profiles: Protein-Protein Similarity. Gene Set - HEK 293T HEK 293T Gene Set Genes 1391 genes with high or low expression in HEK 293T relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset. An adult tissue-specific stem cell in its niche: A gene profiling analysis of in vivo quiescent and activated muscle satellite cells. Please wait . This article focuses on the updates to BioGPS since our last paper (2013 database issue). cell line. However, the function of this glycoprotein and its involvement in cell regulatory cascades are still poorly understood. 2016; 44:D313-D316. . It has the same interface and functionality as the main BioGPS portal, but users can search genes within the exRNA scope, display a set of exRNA related resources, and explore exRNA-specific expression profiles. S1 Fig: Validation of the cell type origin of non-hematopoietic samples.Gene expression for cell type-specific genes as determined by microarray gene expression is shown. However, its intricate. PDF | Recurrent implantation failure (RIF) is an extremely thorny issue in in-vitro fertilization (IVF)-embryo transfer (ET). Conventional microarrays as well as real-time PCR are able to detect existing miRNAs, in which inactive miRNAs that hardly contribute to gene silencing may be also . Description. Geiger Laboratory; Weizmann Institute of Science; Ma'ayan Laboratory of Computational Systems Biology; Icahn School of Medicine at Mount Sinai; We collected 9 breast cancer epithelial cell lines and 5 tumour sampes from which epithelial cells were sorted and enriched using BerEp4 antibody coated beads. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002134) Similar Terms: Downloads & Tools 499 genes with high or low expression in GP2D relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset. However, few systematic studies for chimeric RNAs have been conducted in neuroendocrine prostate cancer (NEPC). BioGPS and GXD: mouse gene expression data-the benefits and challenges of data integration Authors Martin Ringwald 1 , Chunlei Wu , Andrew I Su Affiliation 1 The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA. Using Affymetrix microarrays we compared in vitro gene expression in parental IGROV-1 and TOV21 cells (high CXCR4 expression) with TOV112D and SKOV-3 cells (low CXCR4 expression). . Conclusion: Variations in gene . It was validated as a functional repressive element by the Sharpr-MPRA technique (Systematic high-resolution activation and repression . The following genes are involved in . A immortal human breast-derived cell line cell that has the characteristics: Human cell line derived from breast adenocarcinoma. ; Achilles Cell Line Gene Essentiality Profiles ( 22-24 ) BioGPS Cell Line Gene Expression Profiles ( 1, 25, 26) CCLE Cell Line Gene CNV Profiles Entrez Gene Summary for LOC125467747 Gene. Symbol Name Standardized Value; NAT2 . As a step toward understanding the complex differences between normal and cancer cells in humans, gene expression patterns were examined in gastrointestinal tumors. a) Using gene expression profiles of cancer cell lines and corresponding metastatic potential scores from the MetMap data, we built machine learning (ML) models to find features associated with . Purpose Specific gene fusions and their fusion products (chimeric RNA and protein) have served as ideal diagnostic markers and therapeutic targets for cancer. SCIENCE It was validated as a functional repressive element by the Sharpr-MPRA technique (Systematic high-resolution activation and repression . If an over-expression experiment is warranted, a cell line with a low endogenous expression level of the gene of interest is required. BioGPS is a free extensible and customizable gene annotation portal, a complete resource for learning about gene and protein function. Human cervix carcinoma established from the epitheloid cervix carcinoma of a 31-year-old black woman in 1951. PTEC-specific expression is shown for PAX8, KCNIP1, KCNJ16 and FXYD2; HUVEC-specific expression is shown for VWF, CDH5, ESM1 and CLEC14A; small intestine-specific expression is shown for OLFM4, RBP2, FABP6 and FAM3B. WikiZero zgr Ansiklopedi - Wikipedia Okumann En Kolay Yolu . MD MB231: MDA MB435: Was originally considered to be a breast cancer cell line but has since been identified as a melanoma cell line. a Gene expression profile of il-11 KD #1 and cas9 . Abstract BioGPS (http://biogps.org) is a centralized gene-annotation portal that enables researchers to access distributed gene annotation resources. Incubation of BMP7 with MCL cell lines increased their resistance to bortezomib and cytarabine, while inhibition of BMP7 expression by siRNA correlated with increased cell death linked to drug application. Here, we analyze the effect of age and CMV seropositivity on the expression of CD300a and CD161 inhibitory receptors, and T-bet and Eomes transcription factors in NK cell subsets defined by the expression of CD56 and CD57. Please wait . | Find, read and cite all the research you . This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. TKG0479 (Deposited from Tohoku Univ.). CiteSeerX - Scientific documents that cite the following paper: Cloned human neuropeptide Y receptor couples to two different second messenger systems. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans (2015) et al. BioGPS Cell Line Gene Expression Profiles: Protein-Attribute Table. mRNA expression profiles for the NCI-60 panel of cancer cell lines. A total of 22 tissues (bone marrow, cerebellum, colon, cortex, fetal brain, heart, kidney, liver, lung, pancreas, prostate, salivary gland, skeletal muscle, small intestine, spinal cord, spleen, stomach, testes, thymus, thyroid, trachea and uterus) and 2 cell lines (HeLa and SH-SY5Y) were examined. BioGPS: building your own mash-up of gene annotations and expression profiles. . CD300a is expressed by the majority of NK cells. Cells, Cultured Cell Line Cell Nucleus HeLa Cells Tumor Cells, Cultured Cell Line, Tumor Chromatin Fibroblasts Liver 3T3 Cells Embryo, Mammalian COS Cells Kidney Embryo . Gene Set Enrichment Analysis (GSEA) of those genes which were differentially expressed between cell lines with high versus low CXCR4 expression revealed evidence for a cell autonomous signaling network involving CXCR4, TNF-a, IL6 and Notch pathways in ovarian cancer cells. and NK cells exhibited an activated profile. BioGPS Cell Line Gene Expression Profiles. Transcriptome profiling also informed HOXA1's ability to potently down-regulate expression of microphthalmia-associated transcription factor (MITF) and other genes required for melanocyte differentiation, suggesting a mechanism by which . Comparison 1 comprised EVT, HTR-8/Svneo and SGHPL-5 vs choriocarcinoma cells (ACH-3P, BeWo, JEG-3). THP-1 cells had been cultured in RPMI medium 1640 containing the identical dietary supplements. transcription factor mrna expression. Dataset. Gene-expression profiling of 718 patients with DLBCL was done, for which RNA sequencing data and clinical covariates were obtained from Reddy et al. BioGPS Cell Line Gene Expression Profiles: Category: transcriptomics Type: cell line: Description: Human caucasian skin melanoma cell line; established from a 24 year old Caucasian female. MyGene.info 2016 Year-end review Here we show a positive correlation between the level of CD133 plasma membrane expression and the proliferative activity of cells of the Caco-2, HT-29 . Nucleic Acids Res. Overexpression and knock-down are two popular methods for characterizing the biological roles of a gene of interest. CELL LINE CANCER CELL TYPE; GSM714346: MCF7: non-aggressive: GSM714347: 231MFP: aggressive: GSM714348: OVCAR3: non-aggressive: GSM714349: SKOV3: aggressive: GSM714350: MUM2C: non-aggressive: GSM71435: C8161: aggressive: GSM714352: LNCAP: non-aggressive: GSM714353: DU145: aggressive: GSM714354: PC3: aggressive Cell tradition KBM-7 cells had been cultured in Iscove's Modified Dulbecco's Medium (IMDM) (Thermo Fisher Scientific) supplemented with 10% heat-inactivated fetal calf serum (FCS) (Thermo Fisher Scientific) and 1% penicillin-streptomycin-glutamine answer (Thermo Fisher Scientific). cell line: Description: Human T cell leukemia, established from the peripheral blood of a 14-year-old boy with acute lymphoblastic leukemia (ALL) at first relapse in 1976; often this cell line is called JM (JURKAT and JM are derived from the same patient and are sister clones), occasionally JM may be a subclone with somewhat divergent features. high expression Show entries Filter Showing 1 to 20 of 1,020 entries Previous 1 2 3 4 5 51 Next low expression Show entries Filter Showing 1 to 20 of 371 entries In this study, we explored the landscape of chimeric RNAs in different types of prostate cancer (PCa) cell lines and aimed to . Additional sub-portals have been created focusing on circadian rhythm studies and primary cells gene expression . transcriptomics. doi: 10.1093/nar/gkv1104 . CD133 is an extensively studied marker of the most malignant tumor cell population, designated as cancer stem cells (CSCs).
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